I've encountered the same problem since recently stumbling upon a copy of FO2.
My rig's set up like this:
Win XP Home Ed. (SP2)
T2400 @ 1.83Ghz (essentially 3.6Ghz)
1GB RAM
Utilising ATI's Mobility Radeon X1300 (256mb)
DirectX 9.0c
I've tried the solutions as mentioned; manual...