I think Bethesda at least put some thought into honoring the fallout bible and the idea of psychotropic drugs is great. affecting your vision and sending you crazy is a fantastic touch. Now I wonder if their attention to detail will extend to you not being affected by the drugs if you are wearing power armor as soon as you enter
The big problem with this great idea, however, is that Bethesda have a history of thinking of an idea, thinking it is cool, and just abstractly applying it without logic. This reminds me of one time in Oblivion when I stumbled into a cave.. it was full of vampires. As soon as I killed them all, I was wondering why they were all here, what was the point. Hey guess what, it was just a meaningless dungeon crawl with no logic. Just dark caves and vampires. Leaving it up to our imagination is fine... but at least have some context about how this nest of vampires came to be, or how they are starting to terrorize the surrounding areas. Cool idea, no logic or context. I got the feeling like I was playing something without soul.
Same applies here. Great idea (lifted from the Fallout Bible), but as everyone said before... how would you have time to eat and procreate (for 200 years no less!). Also, The idea that some randoms came in, got crazy and put on vault 106 suits is a little far fetched.
Great idea... no context... making it a hollow attempt at fallout imitation