Kids who grew up on the Tits! series (developed for PS3, Xbox, Gamecube^2, and later UltraMegaPS4) will laugh at the fucking lame 2D graphics of the original games, and be baffled by the fact the game doesn't tell them exactly where to go, how to find it and what to do. They'll also point out there's not enough tits, and based on that, proceed to declare the game gay.
The irony is that the Tits! series actually contains parts of the Fallout setting, since the maker of Tits! bought the Fallout license off Interplay when it went bankrupt in 2004.
The first Fallout fans will go senile and move to nursery homes.
Well, that's more like 2030, but anyway.